Wasting (Cachexia)
Cancer frequently leads to widely recognized but poorly understood syndrome known as cachexia. The manifestations of this syndrome are weakness, loss of weight and appetite (anorexia). The patient appears ill and emaciated. The cause of anorexia remains complex and unclear. Muscle biopsies from breast and colon cancer patients show fat content of the muscles to be half of non-cancer patients. There is also an increased break down of proteins in the muscles.